Lemierre's syndrome

Authors

Abstract

Introduction: Lemierre's syndrome is a rare infectious disease characterized by septic thrombophlebitis of the internal jugular vein, usually secondary to oropharyngeal infections. The primary pathogen is Fusobacterium necrophorum, a gram-negative anaerobe that produces toxins that facilitate hematogenous dissemination, causing septic embolisms in the lungs, bones and joints, liver, and central nervous system.

Objective: To analyze the pathophysiology, clinical manifestations, diagnosis, treatment, and prognosis of Lemierre syndrome.

Methods: Literature indexed in PubMed and MEDLINE between 2000 and 2023 was reviewed.

Conclusions: Despite the reduction in mortality with antibiotic use, Lemierre's syndrome remains associated with significant morbidity, with serious complications occurring in up to 50% of cases. Early identification and timely treatment are key to improving the prognosis.

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Author Biographies

Charbel Kamil Faizal Gómez, Universidad de La Sabana

Médico Universidad de la Sabana

Maria Camila Solano Velandia, Universidad de Los Andes, Fundación Cardioinfantil

Fisioterapeuta, candidada a mágister en Epidemiología

Published

2025-07-11

How to Cite

1.
Faizal Gómez CK, Solano Velandia MC. Lemierre’s syndrome. Rev Cubana Otorrinolaringol Cirug Cabeza Cuello [Internet]. 2025 Jul. 11 [cited 2025 Jul. 15];9:e_462. Available from: https://revotorrino.sld.cu/index.php/otl/article/view/462

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Section

Artículo de revisión, revisión sistemática o metanalítica